Description
Kisspeptin-10 Reference Material | GPR54 Agonist
Kisspeptin-10 (KP-10; Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2; MW 1,302.49 g/mol) is the most potent naturally occurring GPR54 receptor agonist. GPR54 (KISS1R) is expressed on GnRH neurons in the hypothalamus, and Kisspeptin/GPR54 signaling is recognized as the primary upstream regulator of GnRH neuron activation — a discovery that has transformed understanding of reproductive neuroendocrinology.
Laboratory Research Applications
- GPR54 receptor binding kinetics and GnRH neuron activation studies
- LH surge triggering and ovulation timing research models
- HPG axis upstream regulation and reproductive neuroendocrinology
- Puberty onset timing and KISS1R signaling research
- Male reproductive axis — testosterone and LH pulsatility studies
- KISS1 as a metastasis suppressor — cancer biology assays
Specifications
- Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
- Molecular Weight: 1,302.49 g/mol
- Form: Lyophilized powder
- Purity: ≥98% (HPLC verified)
- Storage: 2–8°C; -20°C long-term
For laboratory research use only. Not for human or veterinary use.






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